Okay, I asked a few people in different teams and while unverified, my (and my colleagues') understanding is this: the targeting does continue to work, but the content is now shared organically among the commenter's network because of the activity they took on the content, which could result in international interaction.
Think of it as targeted to followers of your page but not targeted for organic activities against the post.
It's hard for me to test this as organic targeting requires 300 followers and all my dummy accounts have less than that. Please reach out, if you need a soundboard or want to discuss further.
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